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Dear Catherine, I have noticed that if I take a regular sinemet too close to bedtime it gives me powerful "lucid dreams" which I find very disturbing. I take my last regular sinemet four hours before I go to sleep. I do take one CR sinemet (which iI have found has a minimal symptom relief effect) at bedtime so as to help me sleep, and this does not tip me into lucid dreams. Good luck, David >From: Lee Wu <[log in to unmask]> >Reply-To: Parkinson's Information Exchange Network ><[log in to unmask]> >To: [log in to unmask] >Subject: Re: Psychosis in Parkinsons >Date: Wed, 16 Nov 2005 14:19:49 +1100 > >Dear Catherine, > Not sure about the Sinemet causing psychotic episodes, for me it was the >add on anti parkinsonian meds ie agonist drug Permax. When stopped my >clarity of thought ability to concentrate etc returned although that's >different to psychosis. > I can recall a rather ugly episode when I stopped Tasmar ( a COMT >inhibitor) abruptly and was convinced of things that hadn't even happened >so I'm guessing that was a psychotic episode. Maybe it was the agonist >Permax but the pharmacy was unable to obtain Tasmar and this was day three >of suddenly having none. > Hope this helps, a Neurologist told me that Sinemet is the gold standard >drug and the other drugs (with my history) are not worth the risk of taking >due to behavioural issues. > Lee > >Catherine Roberts <[log in to unmask]> wrote: > My mother has rather advanced Parkinson's and has been suffering quite >serious psychotic delusions as a side effect (presumably) of the sinemet. >Is >anyone aware of any non-surgical treatment alternatives that would address >the Parkinson's symptoms while minimizing the psychosis? I am aware of the >role of dopamine in all of this, but she has been trying to find the right >balance between the sinemet and the antipsychotic meds used to try and >control the psychosis for a long time with only limited success. If there >are any other treatment alternatives out there I would be grateful for any >information you could pass on. Thanks very much. > >---------------------------------------------------------------------- >To sign-off Parkinsn send a message to: >mailto:[log in to unmask] >In the body of the message put: signoff parkinsn > > > > >--------------------------------- > ____________________________________________________ >--------------------------------- >Do you Yahoo!? > >---------------------------------------------------------------------- >To sign-off Parkinsn send a message to: >mailto:[log in to unmask] >In the body of the message put: signoff parkinsn > Never miss an Instant Message - Yahoo! Messenger for SMS ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn