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 Gold nanoparticles and radiation may halt Alzheimer's
 Washington: A team of researchers from Chile and Spain has claimed that a
combination of gold nanoparticles and radiation may halt or slow Alzheimer's
disease progression without harming healthy brain cells.

According to their study, to be published in the American Chemical Society's
Nano Letters, the technique - a type of molecular surgery - has the potential
to destroy beta-amyloid fibrils and plaque - hypothesized to contribute to
the mental decline of Alzheimer's patients.

Using test tube studies, the scientists attached gold nanoparticles to a group
of beta amyloid fibrils, incubated the resulting mixture for several days and
then exposed it to weak microwave fields for several hours. The energy levels
of the fields were six times smaller than that of conventional cell phones
and unlikely to harm healthy cells.

The fibrils subsequently dissolved and remained dissolved for at least one
week after being irradiated, indicating that the treatment was not only
effective at breaking up the fibrils but also resulted in a lower tendency of
the proteins to re-aggregate.

The same approach also holds promise for treating other neurodegenerative
diseases that involve protein aggregation, including Parkinson's and
Huntington's, said lead researcher Marcelo J. Kogan, adding ,the approach is
similar to that of another experimental technique that uses metallic
nanoparticles to label and destroy cancer cells.

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