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Nick wrote:> sinemet/comtan dose at 6pm. It didn't kick in by 7:10pm, so she took one > more sinemet cr. It finally kicked in at 7:40pm. > > Any idea why it didn't kick in 2 times? Sinemet is absorbed in the duodenum. As you probably know, protein blocks the metabolism of Sinemet. It is possible that your wife has very slow peristalses due to her PD and the food took a longer time to move through her stomach and duodenum, thus preventing the absorption of Sinemet. --------- God bless Mary Ann (Cg Jamie 66/26 with PD) -- No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.1.375 / Virus Database: 267.14.21/236 - Release Date: 1/20/2006 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn