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Hi Amanda, I have a Susan Greenfield book, Understanding the Mind. I totally agree in that she writes in a simple/understandable way. I just caught a few minutes of a recent series on TV and as she was explaining something she said,".....like a chemical soup...", "constantly changing, second by second, based on what it's receiving". This really crystalised my thoughts and in particular one: medication/s and dosage. I would say it's totally impossible to know how much to take and when because the Mind [Brain] is constantly changing the [recipe] chemical soup; and I'd go further and say that the meds spoil rather than enhance the recipe. I have been doing a lot of research of material to support my theory that PD is manmade, from earliest times [Essentially environmental toxins, e.g . Metals, in particular Lead ad Mercury] through the Middle-ages, to the dawn of the industrial revolution - which is when the number of cases began to increase and Dr. James Parkinson wrote his 'Essay on the Shaking Palsy'.1817. The number of cases has steadily grown and, I would say, 'accelerated' in the last 30-50 yrs. I don't think it's just a coincidence that in the same period the use of Chemicals in Agriculture, the Food processing industry -maybe even personal hyginge and laundry products; at the beginning of the 1900's it was a block of soap, scented or carbolic, and now the number of products take up several aisles in a supermarket - and Industrial Chemicals. We are supposed to be living and benefitting from the Technology revolution; many do and many don't; they pay the price (like us) to keep the wheels of industry oiled. We are an acceptable statistic and in turn have become a signicant source of revenue for that other unregulated profit focussed industry, Pharmaceuticals. It's almost 200 years since Parkinson's Essay and there's still no cure. Why? Keep smiling, Marco ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn