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Parkinson's Disease Clinical Trials will Include Co-Enzyme Q10 (CoQ10) 
Creatine Minocycline and GPI-1485 Treatment Options
February 26th 2006
Parkinson's Disease Clinical Trials will Include Co-Enzyme Q10 (CoQ10) 
Creatine Minocycline and GPI-1485 Treatment Options  Coenzyme Q-10
   The Government is looking at substances that may offer hope in slowing the 
progression of Parkinson’s disease, as opposed to just treating the symptoms.  
Various compounds will be tested including Co-Enzyme Q-10 (CoQ10), creatine, 
minocycline and GPI-1485.  
 The National Institutes of Health (NIH) is finalizing plans to enroll 
hundreds of early-stage Parkinson’s patients in this study.  An earlier study 
funded by the NIH found that creatine and minocycline may warrant further 
consideration.  Dr. Karl Kieburtz of the University of Rochester told the 
World Parkinson Congress last week that while the news is encouraging, the 
results do not demonstrate that these agents are effective in Parkinson’s 
disease.  His results will be published the March 14 issue of Neurology.  
 The National Institute of Neurological Disorders and Stroke (NINDS) of the 
National Institutes of Health (NIH) have organized a nationwide multi-center 
effort called NET-PD (Neuroprotection Exploratory Trials in Parkinson's 
Disease).

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