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  Performance enhancing drug could help stroke victims

Friday, 3rd March 2006, 12:08
  Category: Healthy Living
  LIFE STYLE EXTRA (UK) - A KIDNEY hormone once used by drugs cheat athletes 
to boost muscle power could save the brain cells of stroke victims.

Researchers hope EPO (erythropoietin) may also reduce brain damage from other 
neurodegenerative diseases such as Alzheimer's and Parkinson's.

The natural hormone works by increasing the production of red blood cells and 
delivering oxygen to muscles. It was banned by the International Olympic 
Committee in 199O after its abuse by athletes.

Dr Joanne Marsden, of Kings College Hospital, London, says EPO, which is 
already used to treat chronic kidney failure and anaemia, must be considered 
for other illnesses.

Writing in the Annals of Clinical Biochemistry, she said: "The discovery that 
EPO is present in other tissues in the body - eg endothelial (blood vesels), 
myocardial (heart) and neural (brain) cells has led to suggestions it may 
have a beneficial effect on these cells and hence function as an anti 
inflammatory and neuroprotective agent.

"There is increasing evidence EPO may have a beneficial effect in Parkinson's 
disease and other diseases associated with the central nervous system."

Although the use of the hormone has side effects such as hypertension and 
thrombosis, Dr Marsden said the "clinical benefits" of it for other 
treatments cannot be ignored.

She added: "There is an increasing amount of evidence based literature that 
demonstrates the usefulness of EPO as a neuroprotective agent at the site of 
injury.

"Consideration must be given to its use in other clinical areas where research 
shows there is benefit to patients."

  Copyright © 2006 National News +44(0)207 684 3000

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