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David, In 2000 My first half/dose of a 50/200 (I think) pill worked great, but never again, even though I continued with 3 pills a day for a year. Yes, I tried CR, carbo/levadopa and again in 2003 after my DBS tried Comtan and Sinemet and the generic to no avail. Crazy, huh? Since I couldn't see any benefit and in my trials after DBS started getting abdominal twitching with no concomitant improvement in movement I couldn't see the point in taking it. But that first half dose really made me think it would work. I still have some 50/200 pills with a discard date of 11-06 so who knows I might break a pill in half and try it again, but I don't like those twitches, they stopped when I stopped the medication after trying it again in 2005 for my new neuro in AZ. Ray---- Original Message ----- From: "DAVID LEWIN" <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, March 27, 2006 7:20 AM Subject: Re: Parkinson's Disease May Be Treated By Electric Current > Dear Ray, > How high was the dossage of Sinemet that you took? How long did you take > Sinemet? Have you ever gone back and taken it again? In the early > stages > of my PD, Sinemet had NO Effect on my functionality. I stopped taking it. > It was only later when I returned to taking it at a high dossage (25/100 > ten > pills a day) that I noticed that effected my body. Regards, David > > >>From: rayilynlee <[log in to unmask]> >>Reply-To: Parkinson's Information Exchange Network >><[log in to unmask]> >>To: [log in to unmask] >>Subject: Re: Parkinson's Disease May Be Treated By Electric Current >>Date: Sun, 26 Mar 2006 13:19:57 -0700 >> >>thanks Maryse, this sounds less intrusive than DBS. I always wondered why >>electricity could help my tremors (which are returning I'm sorry to >>report) >>when I lack dopamine. Ray >>----- Original Message ----- >>From: "M.Schild" <[log in to unmask]> >>To: <[log in to unmask]> >>Sent: Saturday, March 25, 2006 11:18 PM >>Subject: Parkinson's Disease May Be Treated By Electric Current >> >> >>>Parkinson's Disease May Be Treated By Electric Current >>>This Article >>>Also Appears In >>>Neurology/Neuroscience >>> >>>Article Date: 25 Mar 2006 - 0:00am (UK) >>> >>>A simple and efficient method that facilitates Parkinson's disease >>>treatment >>>has been developed by researchers of the Institute of Human Brain, >>>Russian >>>Academy of Sciences. Influence of feeble electric current on the brain >>>via >>>electrodes laid on the head skin - the so-called transcranial electric >>>polarization (TCEP) - reduces muscle tone and partially restores >>>patients' >>>movements. In combination with antiparkinsonian drug intake, TCEP reduces >>>their side effect. >>> >>>Parkinson's disease is a chronic progressive degenerative disease of the >>>central nervous system. Its main symptoms are - voluntary movements >>>disorder, >>>increased muscle tone (rigidity) and trembling (tremor). The disease was >>>for >>>the first time described by an English physician James Parkinson in 1817 >>>in >>>his "Essay on Shaking Palsy". The origin of the disease has not been >>>fully >>>investigated yet. >>> >>>Today, Parkinson's disease is no longer the destiny of elderly people, >>>young >>>people become increasingly its victims. This was declared by Igor >>>Zavolokov, >>>head of neurology department, clinics of the Institute of Human Brain, >>>Russian Academy of Sciences. According to him, such conclusion was made >>>by >>>the St. Petersburg neurologists based on their experience of patient >>>management. "Parkinson's disease is rather widespread, said the >>>physician, >>>about 1 percent of people older than 60 and about 5 percent of people >>>older >>>than 80 suffer from it, however, recently the disease is more and more >>>often >>>registered with the 30-year old patients. Not long ago, a 19-year old >>>girl >>>was diagnosed with this disease." According to the researchers' opinion, >>>this >>>situation is due to increasing negative impact of the environment and >>>genetic >>>anomalies accumulation. >>> >>>The drugs that parkinsonism patients have to take lifelong often have >>>strong >>>side effects and therefore do not relieve the patient's state too much. >>>Besides, the drugs lose their effectiveness with time. That is why >>>researchers and physicians are in constant search for new remedies. >>> >>>Transcranial electric polarization may become one of such remedies, >>>according >>>to the opinion of researchers from the Institute of Human Brain, Russian >>>Academy of Sciences, St. Petersburg. The experimental group involved 110 >>>patients with stages of Parkinson's disease from 1 to 4, 80 patients were >>>included in the main group where TCEP was applied, and the remaining 30 >>>made >>>the reference group and received only drugs. The patients from the main >>>group >>>did not give up the drugs either but in addition they received three to >>>four >>>sessions of electric therapy every other day. Continuous current of 2 >>>milliampere acted for 15 minutes via cathode and anode on the head skin. >>>The >>>patients' state was assessed judging by intensity of main symptoms - >>>movement >>>rate, muscle tone and tremor - prior to the sessions and after them. >>> >>>According to physicians' observations, TCEP application resulted in >>>reduction >>>of reduntant muscle tone, increase in movement rate and also decrease of >>>drug's side effects. The only thing TCEP had no influence on was tremor. >>>Nevertheless, these are considerable results. Effectiveness of procedure >>>influence on movements and muscle tone varied from 100 to 63.3 percent >>>depending on the stage of disease. The TCEP session effect remained for >>>half >>>a year to a year. >>> >>>INFORMNAUKA (INFORMSCIENCE) AGENCY >>>http://www.informnauka.ru >>> >>>---------------------------------------------------------------------- >>>To sign-off Parkinsn send a message to: >>>mailto:[log in to unmask] >>>In the body of the message put: signoff parkinsn >> >>---------------------------------------------------------------------- >>To sign-off Parkinsn send a message to: >>mailto:[log in to unmask] >>In the body of the message put: signoff parkinsn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn