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while this press release was most likely issued by the Fox Foundation, the quote using the word "late" came from someone at NeuroDerm - i misread when i attributed it to the Fox Foundation.

"M.Schild" <[log in to unmask]> wrote:  May 14, 2006 - May 20, 2006


Micheal J. Fox Foundation awards funding to Israeli company
May. 14 - NeuroDerm Ltd., based out of Ofakim, Israel, has been awarded
$490,000 by the Michael J. Fox Foundation for Parkinson's research. The
award, made under the foundations clinical discoveries program, will support
clinical work to develop a new transdermal skin patch for continuous delivery
of levodopa, the natural precursor of dopamine, which is deficient in
Parkinson's disease. The development is innovative, as researchers believe
that dyskinesias - disruptive, jerky movements associated with long-term
levodopa therapy - result from the sharp fluctuations in dopamine blood
levels that occur when levodopa is given orally. NeuroDerm's system is based
on a proprietary formulation involving a prodrug, levodopa ester (LDE), which
has been able to maintain steady levodopa levels in animal models. NeuroDerm
believes that their patch should be able to minimize or even reverse
dyskinesias and other disabling late motor complications. "This Clinical
Discovery Program grant is part of our focus on speeding highly relevant
treatments to people living with Parkinson's disease," said Deborah W.
Brooks, president and CEO of The Michael J. Fox Foundation. "We believe that
improved delivery through continuous levodopa administration, such as
NeuroDerm's prospective patch aims to achieve, could potentially result in a
significant improvement in patients' day-to-day lives."

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