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> Data from a mix of employer- and government-funded health plans were used to 
investigate actual treatment patterns for patients initiating pharmacotherapy 
for Parkinson's disease in the United States. Treatment patterns evaluated 
included type of initial therapy and rates and types of adjunctive and 
substitute therapies. The study confirms that levodopa remains the most often 
prescribed initial treatment for Parkinson's disease regardless of age or 
drug benefit coverage. The widespread use of levodopa in young Parkinson's 
patients (<65 years) with private insurance may indicate that physicians are 
not overly concerned about or are not fully aware of the association of 
levodopa with long-term motor complications. It may also indicate that 
currently available alternatives to levodopa are not sufficiently effective 
or well tolerated.
> 
>       J Geriatr Psychiatry Neurol. 2006 Jun;19(2):91-7.   
> 
>  
> Patterns of initial pharmacotherapy for Parkinson's disease in the United 
States.
> 
> Huse DM, Castelli-Haley J, Orsini LS, Lenhart G, Abdalla JA.

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