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Steve - why don't you take sinemet any longer?  DBS?  ?
Nancy deGrazia

rayilynlee wrote:

> Steve, I am no expert on this (especially since I don't take Sinemet any
> more) but I think neuros like to delay our taking carbodopa/levodopa
> due to
> the dyskinesias and other side effects PWP eventually suffer, some
> sooner,
> some later.
> Ray
> ----- Original Message -----
> From: "Steve Rack" <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Sunday, May 21, 2006 7:16 PM
> Subject: Re: Correction on Selegeline's neuroprotection
>
>
>> >The American Academy of Neurology issued new practice guidelines in
>>
>>> April 2006. They stated that based on the research, there is no
>>> evidence yet that any PD treatment has been found to be
>>> neuroprotective. More research is needed.
>>> ...
>>> Results and conclusions:
>>> 1. Levodopa does not appear to accelerate disease progression.
>>> 2. No treatment has been shown to be neuroprotective.
>>> 3. There is no evidence that vitamin or food additives can improve
>>> motor function in PD.
>>> 4. Exercise may be helpful in improving motor function.
>>> 5. Speech therapy may be helpful in improving speech volume.
>>> 6. No manual therapy has been shown to be helpful in the treatment
>>> of motor symptoms, although studies in this area are
>>> limited. Further studies using a rigorous scientific method are
>>> needed to determine efficacy of alternative therapies.>>
>>>
>>> http://aan.com/professionals/practice/guidelines/Neuroprotective_PD.pdf
>>
>>
>> ....
>>
>>>
>>> In a recent meeting, the AAN ( I think) decided that so far there is no
>>> known
>>> neuroprotective medication against PD. ( I cannot find the article)
>>> maryse
>>
>>
>> I found the AAN report interesting for a couple reasons:
>> 1. They make no mention of the clinical studies going on right now (I
>> think:-) of CoQ10 and several other supplements with antioxidant
>> properties.
>>
>> 2. Although Levadopa does not appear to accelerate the disease they
>> now recommend delaying its use in favor of agonists etc. Why?
>>
>> --
>> Steve R.
>> Brattleboro, VT
>>
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