 |
 |
Nancy, I think your question may have been meant for me. My first dose of Sinemet in 2000 helped me tremendously, but never again (it never helped tremors) even though I took it for a year. 2 DBS brain surgeries in 2003 helped tremors and I started it and Comtan again, but since it didn't help and I got dyskinesias I couldn't see the point in continuing it.Ray ----- Original Message ----- From: "Nancy S. deGrazia" <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, May 23, 2006 6:13 AM Subject: Re: Correction on Selegeline's neuroprotection > Steve - why don't you take sinemet any longer? DBS? ? > Nancy deGrazia > > rayilynlee wrote: > >> Steve, I am no expert on this (especially since I don't take Sinemet any >> more) but I think neuros like to delay our taking carbodopa/levodopa >> due to >> the dyskinesias and other side effects PWP eventually suffer, some >> sooner, >> some later. >> Ray >> ----- Original Message ----- >> From: "Steve Rack" <[log in to unmask]> >> To: <[log in to unmask]> >> Sent: Sunday, May 21, 2006 7:16 PM >> Subject: Re: Correction on Selegeline's neuroprotection >> >> >>> >The American Academy of Neurology issued new practice guidelines in >>> >>>> April 2006. They stated that based on the research, there is no >>>> evidence yet that any PD treatment has been found to be >>>> neuroprotective. More research is needed. >>>> ... >>>> Results and conclusions: >>>> 1. Levodopa does not appear to accelerate disease progression. >>>> 2. No treatment has been shown to be neuroprotective. >>>> 3. There is no evidence that vitamin or food additives can improve >>>> motor function in PD. >>>> 4. Exercise may be helpful in improving motor function. >>>> 5. Speech therapy may be helpful in improving speech volume. >>>> 6. No manual therapy has been shown to be helpful in the treatment >>>> of motor symptoms, although studies in this area are >>>> limited. Further studies using a rigorous scientific method are >>>> needed to determine efficacy of alternative therapies.>> >>>> >>>> http://aan.com/professionals/practice/guidelines/Neuroprotective_PD.pdf >>> >>> >>> .... >>> >>>> >>>> In a recent meeting, the AAN ( I think) decided that so far there is no >>>> known >>>> neuroprotective medication against PD. ( I cannot find the article) >>>> maryse >>> >>> >>> I found the AAN report interesting for a couple reasons: >>> 1. They make no mention of the clinical studies going on right now (I >>> think:-) of CoQ10 and several other supplements with antioxidant >>> properties. >>> >>> 2. Although Levadopa does not appear to accelerate the disease they >>> now recommend delaying its use in favor of agonists etc. Why? >>> >>> -- >>> Steve R. >>> Brattleboro, VT >>> >>> ---------------------------------------------------------------------- >>> To sign-off Parkinsn send a message to: >>> mailto:[log in to unmask] >>> In the body of the message put: signoff parkinsn >> >> >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: >> mailto:[log in to unmask] >> In the body of the message put: signoff parkinsn >> >> > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn