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Steve, I am no expert on this (especially since I don't take Sinemet any more) but I think neuros like to delay our taking carbodopa/levodopa due to the dyskinesias and other side effects PWP eventually suffer, some sooner, some later. Ray ----- Original Message ----- From: "Steve Rack" <[log in to unmask]> To: <[log in to unmask]> Sent: Sunday, May 21, 2006 7:16 PM Subject: Re: Correction on Selegeline's neuroprotection > >The American Academy of Neurology issued new practice guidelines in >>April 2006. They stated that based on the research, there is no >>evidence yet that any PD treatment has been found to be >>neuroprotective. More research is needed. >>... >>Results and conclusions: >>1. Levodopa does not appear to accelerate disease progression. >>2. No treatment has been shown to be neuroprotective. >>3. There is no evidence that vitamin or food additives can improve >>motor function in PD. >>4. Exercise may be helpful in improving motor function. >>5. Speech therapy may be helpful in improving speech volume. >>6. No manual therapy has been shown to be helpful in the treatment >>of motor symptoms, although studies in this area are >>limited. Further studies using a rigorous scientific method are >>needed to determine efficacy of alternative therapies.>> >> >>http://aan.com/professionals/practice/guidelines/Neuroprotective_PD.pdf > > .... > >> >>In a recent meeting, the AAN ( I think) decided that so far there is no >>known >>neuroprotective medication against PD. ( I cannot find the article) >>maryse > > I found the AAN report interesting for a couple reasons: > 1. They make no mention of the clinical studies going on right now (I > think:-) of CoQ10 and several other supplements with antioxidant > properties. > > 2. Although Levadopa does not appear to accelerate the disease they > now recommend delaying its use in favor of agonists etc. Why? > > -- > Steve R. > Brattleboro, VT > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn