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> We discovered, essentially accidentally, but via a test, that
> the water
> from a well in our friends vacation house
> contained a large  amount of Manganese, to the extent that a
> black
> deposit would form inside the
> pipes and pump.  Manganese has been implied as a causative
> agent for PD.
> Carline has it, I don't.
> Also the exposure was relatively brief as we were there only
> for various
> holidays. It is probably not related
> to Carline's PD because of the short exposures, but maybe it is
> cumulative. Just a heads up. No
> pesticides in that water.


With manganese, one needs to distinguish between ingested and
inhaled exposures.

Ingested manganese is an essential nutrient.  There is very
little evidence of adverse neurological effects of ingested
manganese.  (See reference below.)

On the other hand, there is massive evidence of Parkinson-like
symptoms resulting from inhalation of manganese fumes or
contaminated dust in occupational situations, such as miners and
welders.  These symptoms typically do not respond to the usual
Parkinson's medications.

For further information, see

http://www.atsdr.cdc.gov/toxprofiles/tp151.html

The first chapter is a relatively plain-language summary.  For
the evidence on neurological effects of ingested manganese, the
discussion begins on page 114 of Chapter 2.

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