 |
 |
> Just to let you know, manganese oxide (in powder form) > is a glaze ingredient used by potters. I have worked alot with > clay and used to use as a colourant on clay sculptures. I would > drop an arbitrary amount of powder into water and then dip a > sponge into this solution to dab onto fired clay. The material > data sheet clearly states that it can be absorbed directly > through > the skin into the nervous system. This fact has caused some > potters to stop using it. > > I do not have pd but always wonder if using it has put me at > risk. I have not done a study of the literature, but, as a precaution, it can't hurt to stop using it. Toxicologically, dermal absorption is very different from ingestion. With ingestion, the digestive tract functions to control the degree of absorption into the blood. With dermal absorption, it goes directly into the blood. > Juut as an aside, my mother did have pd and most of her adult > life > craved liver which of course is high in iron. Is there any > correlation > to iron-rich diet from organ meets and pd? The study cited by Maryse (attached to your message) purports to show a correlation. However, it is unclear what other variables were controlled and what lead to the high intake levels of iron and managanese. See my other comments below. As is frequently the case with this sort of study, we do not know whether the high intakes played a role in causing the disease or whether, alternatively, a predisposition to PD caused the craving for liver, or whether some other factor palyed a role in causing both. Therefore, we can't say that your mother would have been better off to resist her craving. We just don't know. >>>> [Arnie] Ingested manganese is an essential nutrient. There >>>> is very >>>> little evidence of adverse neurological effects of ingested >>>> manganese. >>> >>> >>> [Maryse] it could be risky: >>> >>> [Maryse] >>> http://www.neurology.org/cgi/content/abstract/60/11/1761 >> >> [Arnie] Before drawing any conclusions, one would want to >> know more about >> these populations and, in particular, what led some of them to >> consume a lot more iron and manganese than the rest. Was >> there >> something about their sociological or other lifestyle >> characteristics that would occur disproportionately among >> people >> in this area who consume larger amounts of iron and manganese >> than others? >> >> [Arnie] While I don't have the full article, the abstract >> does not >> mention controlling for other variables, not even smoking and >> alcohol consumption (known to be related to PD risk) or >> correcting for multiple comparisons (where testing a large >> number >> of variables can lead to false positives.) ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn