Welders (from the mangaqnese) are one such example, Physicians/dentists, farmers, for some reason also. \Randy Games to entertain your brain. http://www.stargraphics.com Star Graphics Corp 10943 S Forest Ridge Ln Oregon City, OR 97045 ----- Original Message ----- From: "jcu" <[log in to unmask]> To: <[log in to unmask]> Sent: Friday, June 23, 2006 11:02 AM Subject: Re: Manganese, well water, and PD >I appreciate your advice regarding magnesium oxide, Arnie! > Yes, I have stopped using it...But I wonder...are there specific > professions/occupations that show a high incidence of pd > that you are aware of (like, say, potters or x-ray technicians, > etc.)? Assuming there is an environmental trigger... > > Interesting comments about controlled variables, as well. > > > Regardless, > thanks for your comments. > > joan > > As a footnote, > what is interesting about your post is that I received it > even though I did not receive my own post to the list > (the one you responded to)...not sure why. > > > > ----- Original Message ----- > From: "Arnie Kuzmack" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Friday, June 23, 2006 4:46 AM > Subject: Re: Manganese, well water, and PD > > >>> Just to let you know, manganese oxide (in powder form) >>> is a glaze ingredient used by potters. I have worked alot with >>> clay and used to use as a colourant on clay sculptures. I would >>> drop an arbitrary amount of powder into water and then dip a >>> sponge into this solution to dab onto fired clay. The material >>> data sheet clearly states that it can be absorbed directly >>> through >>> the skin into the nervous system. This fact has caused some >>> potters to stop using it. >>> >>> I do not have pd but always wonder if using it has put me at >>> risk. >> >> I have not done a study of the literature, but, as a precaution, >> it can't hurt to stop using it. Toxicologically, dermal >> absorption is very different from ingestion. With ingestion, the >> digestive tract functions to control the degree of absorption >> into the blood. With dermal absorption, it goes directly into >> the blood. >> >>> Juut as an aside, my mother did have pd and most of her adult >>> life >>> craved liver which of course is high in iron. Is there any >>> correlation >>> to iron-rich diet from organ meets and pd? >> >> The study cited by Maryse (attached to your message) purports to >> show a correlation. However, it is unclear what other variables >> were controlled and what lead to the high intake levels of iron >> and managanese. See my other comments below. >> >> As is frequently the case with this sort of study, we do not know >> whether the high intakes played a role in causing the disease or >> whether, alternatively, a predisposition to PD caused the craving >> for liver, or whether some other factor palyed a role in causing >> both. >> >> Therefore, we can't say that your mother would have been better >> off to resist her craving. We just don't know. >> >> >>>>>> [Arnie] Ingested manganese is an essential nutrient. There >>>>>> is very >>>>>> little evidence of adverse neurological effects of ingested >>>>>> manganese. >>>>> >>>>> >>>>> [Maryse] it could be risky: >>>>> >>>>> [Maryse] >>>>> http://www.neurology.org/cgi/content/abstract/60/11/1761 >>>> >>>> [Arnie] Before drawing any conclusions, one would want to >>>> know more about >>>> these populations and, in particular, what led some of them to >>>> consume a lot more iron and manganese than the rest. Was >>>> there >>>> something about their sociological or other lifestyle >>>> characteristics that would occur disproportionately among >>>> people >>>> in this area who consume larger amounts of iron and manganese >>>> than others? >>>> >>>> [Arnie] While I don't have the full article, the abstract >>>> does not >>>> mention controlling for other variables, not even smoking and >>>> alcohol consumption (known to be related to PD risk) or >>>> correcting for multiple comparisons (where testing a large >>>> number >>>> of variables can lead to false positives.) >> >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: >> mailto:[log in to unmask] >> In the body of the message put: signoff parkinsn >> > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn