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Welders (from the mangaqnese) are one such example,
Physicians/dentists, farmers, for some reason also.
\Randy


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----- Original Message -----
From: "jcu" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Friday, June 23, 2006 11:02 AM
Subject: Re: Manganese, well water, and PD


>I appreciate your advice regarding magnesium oxide, Arnie!
> Yes, I have stopped using it...But I wonder...are there specific
> professions/occupations that show a high incidence of pd
> that you are aware of (like, say, potters or x-ray technicians,
> etc.)? Assuming there is an environmental trigger...
>
> Interesting comments about controlled variables, as well.
>
>
> Regardless,
> thanks for your comments.
>
> joan
>
> As a footnote,
> what is interesting about your post is that I received it
> even though I did not receive my own post to the list
> (the one you responded to)...not sure why.
>
>
>
> ----- Original Message -----
> From: "Arnie Kuzmack" <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Friday, June 23, 2006 4:46 AM
> Subject: Re: Manganese, well water, and PD
>
>
>>> Just to let you know, manganese oxide (in powder form)
>>> is a glaze ingredient used by potters. I have worked alot with
>>> clay and used to use as a colourant on clay sculptures. I would
>>> drop an arbitrary amount of powder into water and then dip a
>>> sponge into this solution to dab onto fired clay. The material
>>> data sheet clearly states that it can be absorbed directly
>>> through
>>> the skin into the nervous system. This fact has caused some
>>> potters to stop using it.
>>>
>>> I do not have pd but always wonder if using it has put me at
>>> risk.
>>
>> I have not done a study of the literature, but, as a precaution,
>> it can't hurt to stop using it.  Toxicologically, dermal
>> absorption is very different from ingestion.  With ingestion, the
>> digestive tract functions to control the degree of absorption
>> into the blood.  With dermal absorption, it goes directly into
>> the blood.
>>
>>> Juut as an aside, my mother did have pd and most of her adult
>>> life
>>> craved liver which of course is high in iron. Is there any
>>> correlation
>>> to iron-rich diet from organ meets and pd?
>>
>> The study cited by Maryse (attached to your message) purports to
>> show a correlation.  However, it is unclear what other variables
>> were controlled and what lead to the high intake levels of iron
>> and managanese.  See my other comments below.
>>
>> As is frequently the case with this sort of study, we do not know
>> whether the high intakes played a role in causing the disease or
>> whether, alternatively, a predisposition to PD caused the craving
>> for liver, or whether some other factor palyed a role in causing
>> both.
>>
>> Therefore, we can't say that your mother would have been better
>> off to resist her craving.  We just don't know.
>>
>>
>>>>>> [Arnie]  Ingested manganese is an essential nutrient. There
>>>>>> is very
>>>>>> little evidence of adverse neurological effects of ingested
>>>>>> manganese.
>>>>>
>>>>>
>>>>>  [Maryse] it could be risky:
>>>>>
>>>>>  [Maryse]
>>>>> http://www.neurology.org/cgi/content/abstract/60/11/1761
>>>>
>>>>  [Arnie] Before drawing any conclusions, one would want to
>>>> know more about
>>>> these populations and, in particular, what led some of them to
>>>> consume a lot more iron and manganese than the rest.  Was
>>>> there
>>>> something about their sociological or other lifestyle
>>>> characteristics that would occur disproportionately among
>>>> people
>>>> in this area who consume larger amounts of iron and manganese
>>>> than others?
>>>>
>>>>  [Arnie] While I don't have the full article, the abstract
>>>> does not
>>>> mention controlling for other variables, not even smoking and
>>>> alcohol consumption (known to be related to PD risk) or
>>>> correcting for multiple comparisons (where testing a large
>>>> number
>>>> of variables can lead to false positives.)
>>
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