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Dopamine-like drug my help Parkinson's
JACKSONVILLE, Fla., July 5 (UPI) -- A U.S. study shows that a drug that mimics
the effects of dopamine causes neurons to develop in the brain where cells
have been lost due to Parkinson's disease.
 The study suggests that drugs that affect dopamine D3 receptors might trigger
new neurons to grow in humans with the disease. Some of these drugs are
commonly used to treat Parkinson's disease, according to Christopher Eckman
and Jackalina Van Kampen of the Mayo Clinic College of Medicine in
Jacksonville, Fla.
 "This is the first study to show that endogenous neurogenesis (development of
new neurons from cells already in the brain) can lead to recovery of function
in an animal model of Parkinson's disease," says Eckman.
 Eckman and Van Kampen are looking at how different doses of the drug
pramipexole and similar drugs affect neurogenesis. Once they identify the
most effective doses in animals, the researchers might be able to test
comparable doses in humans.
 The findings are reported in the Journal of Neuroscience.

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