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I have posted this study into this reply. This is really significant (a 20-year study!). I do believe that this is how/why part of my problem began with PD (that and environmental toxins - insecticides). I have suffered with environmental allergies (and animal dander) for years. This may sound ridiculous, but I can tell when I am going to hve a "bad" day by "swelling" across my brow (usually the bridge between my eyes) and increased rhinitis symptoms. Thanks for sharing this. I will keep an anecdotal diary of my nasal symptoms compared to my PD "off" time to see if I can justify a co-relationship. Peggy Willocks Study abstract below: Sent: Tuesday, August 08, 2006 1:16 AM Subject: Rhinitis link to Parkinson's Rhinitis link to Parkinson's A COMMON allergic condition that causes symptoms of a "permanent cold" has been linked to the development of Parkinson's disease in later life. Scientists found that rhinitis sufferers were three times more likely than average to develop Parkinson's. They believe the association could be due to inflammation triggered by the condition. Previous research has shown that people who regularly take anti-inflammatory drugs such as ibuprofen have a reduced risk of Parkinson's. Inflammatory diseases such as lupus and rheumatoid arthritis were not found to be associated with Parkinson's disease. However, this may only be because of the relatively small numbers of people who have these diseases, said the researchers. United States scientists at the Mayo Clinic in Minnesota, compared 196 people who suffered from Parkinson's with a matched group who did not. Over a 20-year period those with allergic rhinitis were 2.9 times more likely to develop Parkinson's. About 16 per cent of the UK population suffer from rhinitis, which is triggered by indoor allergens such as house dust mites and pet skin flakes. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn