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Stem-cell solution panned
Firm finds a way not to kill embryos
By Matt Crenson, Associated Press

 Robert Lanza, M.D., of Clinton, Mass., vice president of medical and
scientific development at Advanced Cell Technology, in his office at the
company's headquarters in Worcester, Mass., last year. The biotechnology
company has developed a new way of creating stem cells without destroying
human embryos, billing it as a potential solution to a contentious political
and ethical debate. "This will make it far more difficult to oppose this
research," said Lanza." (AP Photo/Julia Malakie)

NEW YORK - Find a way to make stem cells without destroying an embryo and
you might resolve one of the nation's fiercest public debates.
A biotech company seems to have done it. But early signs are that the
scientific achievement is not the slam-dunk solution the company had hoped.
Stem-cell opponents said yesterday that the new method still doesn't satisfy
their objections. And on the other side, many scientists and supporters of
federal funding for the research called the technique inefficient and
politically wrong-headed.
But a spokeswoman for President Bush, who last month vetoed legislation that
would have allowed federal money for embryonic stem-cell research, called it
a step in the right direction.
And Dr. Robert Lanza, an executive with Advanced Cell Technology, which
created the new stem-cell lines, said: "This will make it far more difficult
to oppose this research."
Stem cells have become a Holy Grail for advocates of patients with a wide
variety of illnesses because of the cells' potential to transform into any
type of human tissue, perhaps leading to new treatments. But the Vatican,
President Bush and others have argued that the promise of stem cells should
not be realized at the expense of human life, even in its most nascent
stages.
The new method works by taking an embryo at a very early stage of
development and removing a single cell, which can be coaxed into spawning an
embryonic stem-cell line. With only one cell removed, the rest of the embryo
retains its full potential for development.
The method was described online yesterday in the British journal Nature. The
journal published a similar paper by Advanced Cell Technology last year
demonstrating the technique's viability in mice.
"The science is interesting and important," said John Harris, a professor of
bioethics at the University of Manchester in Great Britain, commenting on
the biotech company's efforts.
But few believe it will resolve the bitter ethical battle over stem-cell
research.
"This will please no one," predicted a longtime critic of the company, Glenn
McGee, director of the Alden March Bioethics Institute in Albany, N.Y.
» About the research
Sounds promising: A biotechnology company has developed a way of getting
stem cells from human embryos without destroying them.

Can't please everybody: Some stem cell opponents say it still isn't
ethically acceptable. Advocates of the research say it is less efficient
than existing methods and distracts from the real debate.

How it works: The company takes an early-stage embryo and plucks a single
cell from it that is then used to generate stem cells.

Some stem-cell researchers complain that the new approach, though it may
hold future promise, simply isn't as efficient as their current method of
creating stem cells. That procedure involves the destruction of embryos
after about five days of development, when they consist of about 100 cells.
Meanwhile, hard-line opponents of stem-cell science argue that the technique
solves nothing, because even the single cell removed by the new approach
could theoretically grow into a full-fledged human. Some also object over
the possibility the procedure could harm the embryo in an unknown way.
The method "raises more ethical questions than it answers," said Richard
Doerflinger of the U.S. Conference of Catholic Bishops.
U.S. law currently bans federal funding of any research that harms human
embryos. A White House spokeswoman said the method's eligibility for funding
could not yet be determined.

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