 |
 |
what we need is a new paradigm - one in which the idea is not "how can we reduce dyskinesias" but "hey, here's an idea! why didn't we think of this before? what if we could come up with something that *didn't cause* dyskinesias? and lose efficacy really fast and cause motor fluctuations? wouldn't that be so cool?" after all, they have been trying to fix dyskinesias (etc.) for almost 40 years - they are still trying (i.e., their efforts have been failing for 40 years) yes, there is research going on into areas other than "bandaids for levodopa" but at my last really rough estimate, there is something in the neighborhood of $1 billion worth of levodopa bandaid studies listed on clinicaltrials.gov (both completed and ongoing, and that is assuming they are all Phase I (i.e., the cheapest) trials - which they are not.) $1 billion is a lot of money to still be spending on something that, while better than nothing, is seriously broken, particularly when that money could be allocated to other therapies - ones that would need fewer bandaids. call it my billion dollar bugaboo. --- Randy L Vinecore <[log in to unmask]> wrote: > The lead researcher in a study of cp101,606 said > that although they are > still looking at the data it looks like this > substance decreases dyskinesia. > But as is often the case with this sort of thing it > might increase the > parkinsons symptoms. I was the third primate (and > the first human) to try > this subtance. It would have to be re-engineered to > be marketed as it has > to be delivered iv in it's current form. > \Randy > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > __________________________________________________ Do You Yahoo!? Tired of spam? Yahoo! Mail has the best spam protection around http://mail.yahoo.com ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn