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This is VERY useful.... I seem to have missed Part I.... Any chance you could send me a copy off list? ATB, Bill mailto:[log in to unmask] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]] On Behalf Of mackenzie Sent: Wednesday, August 30, 2006 12:00 AM To: [log in to unmask] Subject: new blog post Part II of "Levodopa - if this is the "gold standard," we are in trouble" basically, 40 years of research into fixing levodopa's problems has reduced nausea, reduced the frequency of dosing, and added less than an hour of on time per day - oh, and it has also resulted in a four-fold increase in the risk of dyskinesias. be sure to read the package insert if you are contemplating starting a levodopa product - incidence of dyskinesias is 60% higher with sinemet than with levodopa (you would actually have to go to pubmed for that info because sinemet came out so long ago statistics like that have long since been revised out of the product insert); the incidence of dyskinesias is 35% higher with sinemet cr than with sinemet; and the incidence of dyskinesias is 75% higher with stalevo than with sinemet cr. that is not what i call progress. --------------------------------- ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn Get your email and more, right on the new Yahoo.com ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn