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Bruce, welcome to our group.  I took Sinemet and it helped once, took it for
a year with no improvement.  3 years ago I had DBS brain surgeries which
control tremor at expense of losing my voice.   I can barely walk and my
hands are like paws, but I don't take any PD meds at all and live alone.
I'm not pushing DBS but some people have had outstanding results, others not
so good.  You probably know all this being a Prof of Neuroscience, but
wanted you to know first hand it really does help tremor, both essential and
PD.  The problem I have also is with dental work - you can't get drills near
neurotransmitters so I have had extractions and may soon be gumming it.
Ray
----- Original Message -----
From: "Bruce Walmsley" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Thursday, November 23, 2006 3:55 PM
Subject: new member - Bruce


> Hi - I am a Professor of Neuroscience at The John Curtin School of Medical
> Research at The Australian National University in Canberra, Australia. I
> was diagnosed with PD in my late forties - I am now 57. At first I took
> cabergoline, a dopamine D2 agonist. This made little difference to my
> symptoms (mostly tremor). I am now on sinemet, which is great. However,
> over the past 3-4 years I developed severe psychosis - mostly paranoid
> delusions - and was hospitalized a number of times. The psychotic episodes
> were frightening for myself and my family. Luckily for me, my wife is a
> wonderful person and she managed to hold our family together (we have a
> teenage daughter and a teenage son). Tracking back, it appears that the
> dopamine agonist was to blame, because shortly after I stopped taking it,
> I returned to normal with no psychosis. I hope it stays that way !
> I would be interested in other people's experiences with dopamine
> agonists. I am hopeful that research into PD will lead to more effective
> treatments - it looks promising and I am optimistic.
> I am looking forward to interacting with others who have PD.
> Cheers,
> Bruce
>
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