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U.S. lawmakers plan to use the first hours of the new 110th Congress,
convening today (January 4), to assemble legislation to extend Federal
research funding to newly derived stem cell lines. President George Bush
vetoed the measure in July 2006 after it had passed the Senate and House
with wide bipartisan support. The House failed to muster the necessary
two-thirds votes to override the veto, a hurdle supporters hope to surmount
this year.

While details were still being worked out last night, the plan as of press
time is for bill sponsors Reps. Diana DeGette (D-Colo.) and Mike Castle
(R-Del.) to reintroduce an identical version of their "Stem Cell Research
Enhancement Act of 2005" in the House tomorrow (Jan. 5), and for Senators
Thomas Harkin (D-Iowa) and Arlen Specter (R-Penn.) to submit the identical
measure as early as today. The bills will be numbered HR 3 and S 5,
respectively.

"Human embryonic stem cells will be one of the main priorities right out of
the gate," said Jon Retzlaff, legislative affairs director for the
Federation of American Societies for Experimental Biology (FASEB). "One of
the main objectives is to get the DeGette-Castle bill passed in both the
Senate and House, and we could be seeing that by next week," he told The
Scientist.

As currently planned, HR 3 will go to the floor of the House for a vote on
Jan. 11, bypassing committee hearings "because it was truly a bipartisan
bill" when it passed last year, said Brandon MacGillis, spokesman for
DeGette. But S 5 will likely be the topic of hearings in the Senate
Committee on Health, Education, Labor & Pensions (HELP), said Harkin
spokesperson Maureen Knightly. The intention there is to add amendments that
would make the measure more attractive to senators and difficult for Bush to
veto.

"This is one of our top agenda items," Knightly told The Scientist. "We
think there is a good chance to over-ride any veto on the Senate side." The
president is widely expected to veto the measure again on moral grounds.
Last year's veto -- Bush's first and only -- was met with disappointment and
frustration by legislators and biomedical research advocates.

As was the case last year, finding the two-thirds votes in both legislative
chambers to override a veto will not be easy. "It will be very difficult to
get the numbers," Retzlaff said. "It's very close right now." Neither
Retzlaff nor the congressional staffers were willing to discuss the
vote-count at this time.

In the House, 290 votes are needed to override the veto if all members vote
(last year the override failed by 51 votes), while 67 are needed in the
Senate (where only 63 supported the bill last year). Nearly all of the 41
incoming House Democrats support the measure, DeGette told the Denver Post
last month. But many of these freshmen replaced Republicans who had also
supported the measure. The Senate picked up at least three more votes,
bringing that body within one vote of the override.

This year, bill sponsors have assembled an eight-member team of lawmakers --
evenly split between Democrats and Republicans -- to lobby colleagues,
MacGillis said. The measure would make Federal research funding available
for human embryonic stem cell lines derived after Aug. 9, 2001, the existing
cutoff date.

DeGette, Castle, Harkin, and Specter plan to outline their strategy for
enacting the stem cell measure during a press briefing next Tuesday (Jan.
9), MacGillis said.

Ted Agres
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