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Worldwide Parkinson's cases will double in next 25 years
Parkinson's disease in 15 of the world's largest nations will double over
the next generation, according to a study published in the January 30 issue
of the journal Neurology. The study highlights the significant challenge
facing countries with rapidly growing economies, particularly in Asia, many
of which are ill prepared to meet this impending public health threat.
In recent years, a great deal of resources and energy have been focused on
confronting infectious diseases such as HIV, malaria, and tuberculosis. This
is highlighted by high-profile private investments in these areas by
organizations such as the Gates Foundation. However, while infectious
diseases have attracted the greatest attention from international donors, it
is non-communicable chronic diseases, such as Parkinson's, that represent a
far greater burden in terms of economic and social cost to developing
nations.
University of Rochester neurologist Ray Dorsey, M.D., and a team of
researchers examined the projected population growth in the five largest
countries in Western Europe (France, Spain, Germany, the United Kingdom, and
Italy) and the 10 most populous nations worldwide (China, India, Indonesia,
the United States, Brazil, Pakistan, Bangladesh, Nigeria, Japan, and
Russia). They then projected the prevalence of the disease by age group in
each country. Their research estimates that the number of individuals with
Parkinson's disease in these 15 countries will grow from 4.1 to 8.7 million
by the year 2030. While the number of individuals with the disease will
nearly double in the United States to 610,000, the greatest growth will
occur in developing countries in Asia. By 2030, an estimated 5 million
people in China will have the disease.
"The bulk of the growth in Parkinson's disease in the next 25 years will not
be in the United States and Europe but in other places, namely China, where
Parkinson's may not be viewed as a major public health problem," said
Dorsey. "Moreover, this growth will occur in societies where there is very
limited infrastructure in place to diagnose individuals, much less address
their medical needs or the societal impact."
Parkinson's disease is a degenerative disorder of the central nervous system
that impairs motor skills and walking. Despite the fact that the disease is
treatable with a combination of medications, therapy and exercise, many
individuals in the developing world do not receive appropriate care and may
not even be aware of their diagnosis. Dorsey and his colleagues noted that
in door-to-door surveys in Bolivia, for example, none of the individuals who
were found to have Parkinson's disease had ever seen a physician for their
problem.
The growth in chronic diseases such as Parkinson's is one of the unfortunate
byproducts of development. Economic growth and the corresponding
improvements in health care and education are increasing the life expectancy
of individuals in the developing world. In terms of the rise in chronic
diseases, the key factor is not overall population growth but rather the
number of people over age 65 and thus at risk of developing Parkinson's and
other chronic conditions. Furthermore, as income grows, so too does health
care spending which, in turn, increases the duration of illness and the
overall number of people with a particular disease.
Without the proper systems of medical treatment and social support, chronic
diseases can cause significant economic displacement in the form of lost
productivity. According to the World Health Organization, China, India, and
Russia could forego between $200 billion and $550 billion in national income
over the next 10 years as a result of only three chronic diseases: heart
disease, stroke and diabetes. Furthermore, 60 percent of deaths worldwide
are the result of chronic disease, more than double all infectious diseases,
maternal and infant conditions, and nutritional deficiencies combined.
"Understanding and predicting the burden of disease is critical to guiding
future health, social and economic policy," said Dorsey. "The challenge for
these developing countries that currently don't have the infrastructure in
place to care for the small burden they have now is how they will develop
this capacity over time recognizing that the costs will grow." - University
of Rochester Medical Center

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