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January 28, 2007 - February 3, 2007

 Israeli Parkinson's patch completes clinical trial
Feb. 01 -  Israeli company NeuroDerm, Ltd., has completed a pilot clinical
trial of ND0601, the first transdermal skin patch for the continuous
delivery of levodopa. This drug, which is primarily used in oral form, is
the major treatment for Parkinson's disease. Levodopa is the natural
precursor of dopamine, a neurotransmitter deficient in the Parkinson's
disease brain. The main objective of this GCP compliant pilot study was to
assess the pharmacokinetic profile of levodopa in the blood of healthy
volunteers following application of ND0601. "I am excited to have started
the clinical development of ND0601, a transdermal levodopa patch offering
great hope for improving the disabling problems common in advanced
Parkinson's disease patients. ND0601 should provide continuous delivery of
levodopa in a widely accessible form, a highly sought after treatment option
in Parkinson's disease that has been unavailable to date," said Prof. Oded
Lieberman, NeuroDerm's chairman. The trial was funded by The Michael J. Fox
Foundation for Parkinson's Research through its highly competitive 2006
Clinical Discovery Program.

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