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I had the same problem with Stalevo. Joint pain and increased muscle spasms, especially in my lower back. Sstopped taking it after two months and went back to the 25/100 carba/levadopa 200 mg Comtan regimen. Scott Burnett ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn