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I have been on Stalevo for about two + years. I was on 150 5x a day and had to go back to 100 5x a day because of bad dyskensia. I started having trouble at night some time back. I seem to hurt when I try to roll over at night and I wake up nights when my limbs hurting. Also I can't sleep on my back any longer because I feel that all the parts of my body are being pulled in different directions. I am on a test trial for E2007 now and I feel that this medication is not helping my system. Only time will tell. PD affects us all in different ways. Sometimes when I am on an off period I believe my brain is affected and I can't think straight or do simple math. Such fun. Does anyone feel special about having PD? After suffering from this for 15 years I have finally learned that I Need help at times and if a stranger offers help, i can accept it. Pam ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn