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DiaGenic ASA Presents Prototypes of the First Early Bloodtest for Alzheimer's 
Disease at AD/PD 2007
DiaGenic ASA today presented prototypes for its early diagnostic test for 
Alzheimer's disease at the 8th International Conference on Alzheimer's and 
Parkinson's Diseases (AD/PD 2007) at Salzburg, Austria. Based on gene 
expression analysis using peripheral blood as sample material, the DiaGenic 
test demonstrated high sensitivity and specificity on both prototypes. 
"The data presented by DiaGenic suggest that this strategy for biomarker 
discovery may pay off," said Professor Sam Gandy of the Farber Institute for 
Neurosciences, Thomas Jefferson University in the US. "There is a clear need 
for a better and earlier diagnosis of Alzheimer's patients."
 DiaGenic CEO Erik Christiansen commented, "We have now used the informative 
genes identified in previous studies to design and develop customized arrays 
on two different platforms that employ alternate technologies for gene 
expression profiling and validated them using a new and independent patient 
cohort. One is based on microarray technology (CodeLink™ Customized 
Multiassay Bioarrays), while the other relies on RT-PCR technology (TaqMan® 
Low density arrays). The results from both prototypes fully meet the criteria 
for diagnostic use. In case of TaqMan, a 96 gene expression format has been 
developed retaining the high diagnostic accuracy reported by us on previous 
studies."
 Alzheimer's disease is a progressive brain disorder afflicting approximately 
20 million individuals worldwide, with a dramatic rise due to changing 
demographics forecast to 30-35 million by the year 2025. The symptoms and 
also the pathology of AD and other forms of dementia are similar and 
overlapping, making an early and accurate diagnosis extremely difficult. 
Alzheimer's disease is the most costly disease for our societies - more 
costly than both cardiovascular disease and cancer combined. In the US alone, 
direct and indirect costs of caring for AD patients are at least $100 
billion. 
 About DiaGenic ASA 
 DiaGenic is an innovative Norwegian biotechnology company that seeks to 
create value for patients, partners, and investors by developing new and more 
patient friendly methods for early detection of diseases. DiaGenic is 
currently a world leader in analyzing gene expression signatures related to 
disease in easily available clinical samples such as peripheral blood. This 
unique method is based on the principle that even when a disease is localized 
at a specific part of the body, secondary responses, which are also 
characteristic of the disease, can be measured in other parts. Significant 
potential in numerous diseases such as breast cancer and Alzheimer's disease 
has been identified. The company has been granted patents in the U.S. and 
Europe. DiaGenic is listed on the Oslo Stock Exchange. For more information 
visit www.diagenic.com. 
 TaqMan is a registered trademark of Roche Molecular Systems, Inc.

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