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Hi Emily, Initially, age 55, I was treated with Ropinirole (Requip) 2mg x3 times per day. I became drowsy 30 mins after each dose. When I was treated with Lyrica (Pregabalin) for left side stiffness & associated pain I suffered severe drowsiness approx 30 mins after each dose(not to mention wt inc of 2 stone in 12 weeks). After researching Ropinirole online I discovered there was a slow-release version available Stateside - it is awaiting NHS UK approval at present. Over time I have adjusted my daily intake of Ropinirole to: 11mgs taken as 2mg x 2 hours . This has worked for me. I am currently taking Amitriptyline (10mg x 1 dose nightly)instead of Lyrica. This is working well. However, due to poor mucle tone (PD), I have no stamina/endurance & thus find any physical exertion very tiring. Last November (06) I started Chinese acupuncture treatment from Dr Martin Albright @ Beacon Clinic, Malvern UK for general well-being & to combat fatigue & other PD symptoms. Apparently it doesn't work for everyone but for me it has been fantastic!! I hope you find this useful, Angela. -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]]On Behalf Of Emily Jackson Sent: 13 April 2007 12:16 To: [log in to unmask] Subject: hello from new list member Hi there I am joining this list as my father-in-law has Parkinson's. I would like to know more about Parkinson's medicines - what have folks tried, what has seemed to work, etc. My father-in-law, Charles, is interested in finding out if anyone suffers from extreme fatigue and what they do about it. I'm just thankful that something like this exists and look forward to "meeting" some of you and learning more. Thanks Emily ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn