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Antidepressants increase risk of Parkinson's disease

Posted : Sat, 28 Apr 2007 17:56:01GMT

   A new study says that depression could be one of the earliest signs that a
patient might suffer from Parkinson's disease in future. The study examined
if people taking anti-depressant medications were more likely to suffer from
Parkinson's disease than people who were not on the medications.

 The study found that people who were taking antidepressants one year before
they were diagnosed with Parkinson's were twice at risk for developing the
condition as compared to those who were not taking the drugs. The researchers
analyzed a database involving over three million people in the UK and
identified 1,052 people with Parkinson's disease. These people were compared
with 6,634 people not having the disease.

 The researchers also examined the antidepressant use among the Parkinson's
patients. The risk of Parkinson's in patients taking antidepressants was
equal in both men and women irrespective of their age.

 "This should not be interpreted as evidence that antidepressants cause
Parkinson's disease," said Miguel Hernan of the Harvard School of Public
Health. "The relationship is only apparent in the year before the onset of
the disease, which suggests that depression is an early symptom of the
disease."

 The findings of the study were detailed at the 59th Annual Meeting of the
American Academy of Neurology.

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