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In a message dated 25/06/2007 07:01:26 GMT Standard Time, [log in to unmask]  
writes:

Let's  hear it for the land of single malts, haggis, and  selkies!

Kathleen







-----Original  Message-----
From: rayilynlee <[log in to unmask]>
To:  [log in to unmask]
Sent: Fri, 22 Jun 2007 5:41 pm
Subject:  Useable unuseable eggs









Roslin experts  reveal major stem-cell breakthrough 

ALAN RODEN HEALTH REPORTER (  ) 

A MAJOR scientific breakthrough in stem cell research was today  revealed by 

Lothian experts in a move that could lead to huge  advances in medical 

treatment. 

For the first time,  scientists from Roslin have managed to create new stem 

cells from  a clinically unusable human egg. 

In the long-term, the  development could have major implications for research 

into  illnesses such as Alzheimer's, Parkinson's, liver disease and  diabetes 

as well as offering hope to infertile  couples. 

The breakthrough was made by Roslin Cells Limited, a  spin-off company from 

the world-famous Roslin Institute in  Midlothian. 

Until now, eggs used in research that failed to  fertilise - and could not 

develop into a viable human embryo -  were routinely discarded. 

But with a major shortage of embryos  available for research, today's 

announcement means these eggs  could now still be used to produce embryonic 

stem  cells. 

Stem cell researchers can study diseases and develop new  treatments, such as 

drugs for the prevention of illnesses like  cancer. 

Because of their potentially unlimited capacity for  self-renewal, embryonic 

stem cell therapies have been proposed  for regenerative medicine and tissue 

replacement after injury or  disease - although to date, there are no 

approved medical  treatments. 

Speaking at the annual meeting of the International  Society for Stem Cell 

Research in Australia, Dr Paul De Sousa -  Roslin Cells' chief scientific 

officer - said: "Typically up to  30 per cent of eggs in an IVF treatment 

cycle will be unusable as  they fail to fertilise or do so abnormally. 

"These eggs could not  develop into a viable embryo and are therefore 

normally discarded  in routine IVF treatment. 

"Until now, it has been thought that  they are also incapable of producing 

embryonic stem  cells. 

"My team at Roslin Cells has been working with colleagues  at the Central 

Manchester and Manchester Children's University  Hospitals Trust and the 

University of Manchester, to develop  techniques to stimulate these eggs so 

that the cells divide and  develop. 

"Shortly after this process starts, we are able to  extract embryonic stem 

cells. The new cell line which we have  produced in this way, demonstrates 

that embryonic stem cells can  be produced from tissue which was previously 

not considered of  use to stem cell research." 

Funding to support the work carried  out by Roslin Cells and the team in 

Manchester was provided by  the UK Medical Research Council. 

Roslin Cells was established  last year with initial funding of £1.7 million 

from Scottish  Enterprise Edinburgh and Lothian, with support from  Edinburgh 

University and the Scottish National Blood Transfusion  Service. 

The body is designed to consolidate the expertise  developed by the Roslin 

Institute, where scientists created Dolly  the sheep - the first mammal to be 

cloned from an adult  cell. 

Dave Anderson, senior director of operations at Scottish  Enterprise 

Edinburgh and Lothian, said: "This development is  another demonstration of 

the world-class scientific expertise  that we have in Scotland and its 

potential to grow Scotland's  economy. 

"It not only has the potential to transform the lives of  people suffering 

from some of the most debilitating conditions  but also to maintain 

Scotland's position as a global leader in  regenerative medicine." 

This article:  http://edinburghnews.scotsman.com/index.cfm?id=961032007 

Last  updated: 19-Jun-07 14:09 BST 

Rayilyn Brown 

Board  Member AZNPF 

Arizona Chapter National Parkinson's  Foundation 

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 - also rain, taxi-drivers who ask if  you've got any whisky,  plus locals 
who greet unpopular govt. edicts with open contempt., and more  rain.....
 



   

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