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Annette, Mirapex helped my husband get rid of his tremors. It also had a major impact on his depression. It can cause psychosis in high doses - but has been very helpful in riding him of those terrible tremors. ---------- God bless Mary Ann (CG Jamie 67/27 with PD) www.bentwillowfarm.org > My husband has also experienced significant weight loss and a newly-gained > capacity to NOT put on weight since the worsening of his Parkinson's > symptoms several years ago. He currently takes 5 sinemet 25/100 + 5 > sinemet > 50/200 daily. He has severe tremors (bilateral -- arms, hands, legs/feet > + > head) and also has essential tremor (has action, intention and resting > tremors) and he has lost the most weight at the time when his tremors have > been the worst -- I think both because of calories burned through the > constant shaking and because of the fact that bad tremors make it > difficult > for him to eat. L-dopa related nausea/loss of appetite doesn't help. He > also suffers from periodic episodes of severe depression (which are > sometimes associated with total loss of appetite and other times > associated > with an uncontrollable urge to eat tons of ice cream). > > Annette, wife & caregiver of Ken > > On 7/16/07, Nick <[log in to unmask]> wrote: >> >> My wife is a 15 year Parkie. She started losing weight about a year ago, >> and has gone from 105 to 85. She has a good appetite, eats a balanced >> diet. She is still losing weight. She takes amantidine , 2tabs twice a >> day, and 2 sinemet 25/100 before bedtime. Has this happened to any other >> Parkies? Is this directly related to her Parkinson's disease? Please >> help. >> >> Nick >> husband & caregiver >> >> >> ---------------------------------------------------------------------- >> To sign-off Parkinsn send a message to: mailto: >> [log in to unmask] >> In the body of the message put: signoff parkinsn >> > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn