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Creating New Nerve Cells Just Got Easier
By Steven Edwards EmailJuly 31, 2007 | 10:50:44 AMCategories: Neuroscience
Neuron Korean scientists from Yonsei University discovered a new molecule that
aids in the creation of new nerve cells. Creating new nerve cells has been
tricky, because current methods rely on either embryonic stem cells or neural
stem cells obtained from the brain.

This new discovery, to be published in the August 8th edition of the Journal
of the American Chemical Society, shows that a small molecule --
neurodazine -- can induce the generation of new nerve cells from skeletal
muscle fibers, which are easier to obtain in humans. (Muscle biopsy or
drilling into your brain? You decide.)

Initially done on mice cells, the researchers also successfully tested
neurodazine on human skeletal muscle fibers.

The only downside is that while the cells "look" like nerve cells, based on
certain molecular markers, the report doesn't mention any studies testing the
function of these induced-nerve cells in animal models. These tests will be
required before they can be used in humans, so keep an eye out for future
announcements.

Nerve cells have obvious applications for many neurological disorders,
including stroke, spinal cord injury, and Alzheimer's and Parkinson's
disease. Given our aging population, where neurological disorders are most
prevalent, the need for something like this is evident.

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