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NIH Announces Advanced Cell Technology's 'Single Cell Embryo Biopsy
Technique' as a Means to Derive Embryonic Stem Cells to be Considered for
Federal Funding

ACT Applauds NIH Plan to Implement President Bush's Stem Cell Executive
Order
September 20, 2007: 09:00 AM EST


LOS ANGELES, Sept. 20 /PRNewswire-FirstCall/ -- On Tuesday, September 18,
2007, the National Institutes of Health (NIH) announced that it would begin
implementing President George W. Bush's Executive Order to explore methods
to expand the number of approved pluripotent stem cell lines "without
creating a human embryo for research purposes or destroying, discarding, or
subjecting to harm a human embryo or fetus."
This announcement follows an Executive Order issued by President Bush on
June 20, 2007, requiring that "The Secretary of Health and Human Services
... conduct and support research on the isolation, derivation, production,
and testing of stem cells that are capable of producing all or almost all of
the cell types of the developing body and may result in improved
understanding of or treatments for diseases and other adverse health
conditions, but are derived without creating a human embryo for research
purposes or destroying, discarding, or subjecting to harm a human embryo or
fetus."
ACT's groundbreaking Single Cell Biopsy technique was cited by the NIH as an
alternative method in its implementation plan -- a technique successfully
demonstrated by Robert Lanza, M.D., Vice President of Research and
Scientific Development at Advanced Cell Technology, and his team. The NIH
plan calls for "aggressively pursuing an assessment of the potential of
alternative sources of pluripotent stem cell lines, including altered
nuclear transfer; single cell embryo biopsy, and reprogramming, or
dedifferentiation of somatic cells, such as skin cells."
In August 2006, ACT published a paper in Nature documenting the technique
for removing a single cell (known as a blastomere) from an eight-cell human
embryo, and using that cell to generate multiple human embryonic stem cells
without destroying the embryo. The NIH referred to ACT's Nature article in
its implementation plan. In June of this year, ACT announced that it had
successfully produced 4 human embryonic stem cell lines without destroying
the embryos at its lab in Worcester, Massachusetts. The embryo from which
the cell was removed remains cryogenically preserved and remains a viable
embryo. Should the company's blastomere technique satisfy NIH
qualifications, ACT could qualify for federal funding from the NIH.
"Our single cell blastomere technology directly addresses the President's
ethical concerns and, unlike the other potential solutions described in the
order, is available today. We are encouraged by the NIH's willingness to
explore ways to increase the federally approved stem cell lines available
and hope they will consider our technique for federal funding," remarked
William M. Caldwell IV, Chairman and CEO of Advanced Cell Technology. "We
believe that such consideration reflects the will of the American people to
bring novel therapies derived from stem cell research to patients with few
or no alternatives."
About Advanced Cell Technology, Inc.
Advanced Cell Technology, Inc. is a biotechnology company applying stem cell
technology in the emerging field of regenerative medicine. The company
operates facilities in California and Massachusetts.
For more information, visit http://www.advancedcell.com



Rayilyn Brown
Board Member AZNPF
Arizona Chapter National Parkinson's Foundation
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