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I find the neupro patches stick better if I use an alchol swab on the skin. Then a tissue with water to wipe off the alchohol and a dry tissue to make sure the skin is dry. It has helped me. ----- Original Message ----- From: "Nigel Harland" <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, September 17, 2007 12:47 AM Subject: Re: NEUPRO Rotigotine PATCH > Hi, Here is another update for those of you who are interested. I have > been > using Neupro Rotigotine Transdermal patches since May 10th, as an > alternative to Mirapex..I started on the lowest dose 2mg/24hr, and am now > on > the highest dose 8mg/24hrs. The most obvious benefit is a big reduction in > duration and strength of dyskenesia, it is still there, but much less of a > problem. also it means 3 less tablets per day.The negative points are, off > times are now really off, can't walk or get out of my chair, so I have had > to increase the frequency Madopar from 3 times a day to 4 times a day to > try > and counter this. Also I find it is difficult to make the > patches stay in place, I have found that using strips of elasticated > tubular > bandages ensures that they stay on. My Neuro' recently suggested I try > Entacapone as well, in an attempt to prolong the "On" times, but all it > has > done is increase the dyskenesia to an uncomfortable level., so I will stop > taking that. > > Conclusion: On balance I would say it has been worthwhile changing onto > Rotigotine, if only because of the drastic reduction of the hated > dyskenesia., but the increase in severity of "Off " time is a big negative > point. > > Nigel. > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn