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Rick: Several reactions: (1) You don't say that you are depressed. While depression is common in PD, if you are not depressed, you should probably not be taking an antidepressant. If you are depressed, then it is a matter of trial and error to find the best antidepressant for YOU, which will not necessarily be the same as what is best for someone else with PD. (2) Since none of the standard medications seem to affect your symptoms, and since Metoprolol did help with them, you might ask you neurologist to reconsider the diagnosis of PD. There are other forms of parkinsonism, which require different forms of treatment. Do a Google search on "parkinsonism" for additional information. Good luck! ----- Original Message ----- From: "RICK KNITTEL" <[log in to unmask]> To: <[log in to unmask]> Sent: Saturday, January 05, 2008 7:32 PM Subject: Antidepressants > Hello > > I have had symptoms (tremor & shuffle walk) for almost three years and > was diagnosed with PD 16 months ago. Since that time, I have tried > Selegiline, Sinamet, Artane, Mirapex, Baclofen and Neupro patches. None > of these reduced the tremor or improved my walk and all of them had > serious side effects on my digestive system (nausea/reflux to the extent > I could not eat and in some cases could not get out of bed). Another > medication, Metoprolol, for chest pain did lessen the tremor but > aggravated my asthma and liver disease. > > My question is; has anyone experienced depression related to PD and what > medication has been effective? My wife and our family therapist are both > asking me to seriously consider an antidepressant to aid my sleep > depravation/muscle tightness and my primary care physician has prescribed > Ambien. My neurologist/movement disorder specialist has not been willing > to prescribe an antidepressant so far. I see him again on Tuesday. We > depart for three months in Sarasota on 12 January. > > Rick Knittel > South Portland, Maine > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn