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My first question is....do you really have PD??? If none of the PD drugs worked for you there seems to be a glitch in your diagnosis. Essential tremor does respond to Beta blockers (Metoprolol) and is not PD. Since that was your experience, maybe you should seek out a second opinion. As for your depression - there are a host of drugs that do work for that problem that are compatible with PD. Ask your neuro about them. ----------- God bless Mary Ann (CG Jamie 68/28 with PD, died 11/20/07) www.bentwillowfarm.org > > I have had symptoms (tremor & shuffle walk) for almost three years and > was diagnosed with PD 16 months ago. Since that time, I have tried > Selegiline, Sinamet, Artane, Mirapex, Baclofen and Neupro patches. None > of these reduced the tremor or improved my walk and all of them had > serious side effects on my digestive system (nausea/reflux to the extent > I could not eat and in some cases could not get out of bed). Another > medication, Metoprolol, for chest pain did lessen the tremor but > aggravated my asthma and liver disease. > > My question is; has anyone experienced depression related to PD and what > medication has been effective? My wife and our family therapist are both > asking me to seriously consider an antidepressant to aid my sleep > depravation/muscle tightness and my primary care physician has prescribed > Ambien. My neurologist/movement disorder specialist has not been willing > to prescribe an antidepressant so far. I see him again on Tuesday. We > depart for three months in Sarasota on 12 January. > > Rick Knittel > South Portland, Maine > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn