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> I am 65, diagnosed last year, just starting Sinemet. My neurologist > tells me that Sinemet does not induce on-off symptoms or dyskinesias, > and that those would occur with or without it as a result of the natural > progression of PD. This issue arose in discussion of dopamine agonists > pro's and con's and my reluctance to start down the Sinemet road without > knowing where it would lead. She says that favorable reviews of DA's are > due largely to promotional efforts of pharmaceutical companies. I would > be grateful for any thoughts and insights on this. I think she is right about the agonists but on-off symptoms and dyskinesias are a product of dopatherapy. Sinemet or agonists. Here in France, the new guidines are not to prescribe agonists after 65-70. maryse cg John 79,18 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn