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Hello Moneesha and welcome. It does sound like a lot of medications. Couldn't you have the advice of another neurologist, one who specializes in PD? Also, have your husband checked for UTI or any other sort of infection. They are often responsible for rapid progression of confusion Maryse cg JOhn, 79, 19 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn