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Ok thanks. I will. Moneesha On Sat, Mar 22, 2008 at 6:50 PM, Dr. R. Rsjaraman < [log in to unmask]> wrote: > Hi Moneesha: > I think you should test for the thyroid function too. Usully this also > goes > down several years head of time. > R. Rajaraman > ******************** > ----- Original Message ----- > From: "Moneesha Sharma" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Saturday, March 22, 2008 4:12 AM > Subject: Re: Your Nose and PD > > > > This was certainly the case with my husband. Some years previous to his > > diagnosis of PD, we were surprised to find that he was gradually losing > > his > > sense of smell. We put it down to the fact that he had been a smoker in > > his > > younger days. I found out about the link between PD and a loss of the > > sense > > of smell when I was searching the net for symptoms of PD before we > > actually > > went to the doctor. He had all the initial symptoms including a loss of > > the > > sense of smell. > > Moneesha Sharma > > > > > > On Sat, Mar 22, 2008 at 6:58 AM, rayilynlee <[log in to unmask]> wrote: > > > >> Your nose may warn about onset of Parkinson's > >> > >> From correspondents in Washington, United States, 11:31 AM IST > >> > >> An impaired sense of smell occurs in the earliest stages of Parkinson's > >> disease (PD) and there is mounting evidence that it may precede motor > >> symptoms by several years, according to a study. > >> The study, by researchers at the Pacific Health Research Institute in > >> Hawaii, found that smell impairment can precede the development of PD > in > >> men > >> by at least four years. > >> Findings of the study have been published in the latest edition of the > >> Annals of Neurology, the official journal of the American Neurological > >> Association. > >> Led by G. Webster Ross of the VA Pacific Islands Health Care System and > >> the > >> Pacific Health Research Institute in Honolulu, Hawaii, the study > included > >> 2,267 men who received an olfactory test and were followed for up to > >> eight > >> years to find out if they developed PD. During the course of follow-up, > >> 35 > >> men developed the disease. > >> The results showed that a smell identification deficit could predate > the > >> development of PD by at least four years, although it was not a strong > >> predictor beyond this time period. > >> A decreased ability to identify odours was associated with older age, > >> smoking, more coffee consumption, less frequent bowel movements, lower > >> cognitive function and excessive daytime sleepiness, but even after > >> adjusting for these factors, those with poor odour identification had a > >> five > >> times greater risk of developing PD. > >> The pathology of smell impairment in PD is not completely understood, > but > >> nerve loss and the formation of Lewy bodies, abnormal clumps of > proteins > >> inside nerves cells that are thought to be a marker of PD, are known to > >> take > >> place in the olfactory structures of patients with the disease. > >> The authors note that one study involving brain dissection of dead > >> patients > >> with neurological disease found that olfactory structures are the > >> earliest > >> brain regions affected by Lewy degeneration, which supports the idea > that > >> an > >> impaired sense of smell could be one of the earliest signs of the > >> disease. > >> (Staff Writer, (c) IANS) > >> > >> Rayilyn Brown > >> Board Member AZNPF > >> Arizona Chapter National Parkinson's Foundation > >> [log in to unmask] > >> > >> ---------------------------------------------------------------------- > >> To sign-off Parkinsn send a message to: mailto: > >> [log in to unmask] > >> In the body of the message put: signoff parkinsn > >> > > > > ---------------------------------------------------------------------- > > To sign-off Parkinsn send a message to: > > mailto:[log in to unmask] > > In the body of the message put: signoff parkinsn > > > > > > -- > > No virus found in this incoming message. > > Checked by AVG. > > Version: 7.5.519 / Virus Database: 269.21.8/1337 - Release Date: > > 20/03/2008 8:10 PM > > > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto: > [log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn