Does that mean the patches are patchy ? :) - sorry, cheerfulness keeps breaking out. Quoting "[log in to unmask]" <[log in to unmask]>: > UCB advises US-physicians to down-titrate patients on Neupro(R) in view of > out-of-stock situation in the USMARKETWIRE > Mar 20, 2008 BRUSSELS, BELGIUM MARKET WIRE > UCB initiates recall of Neupro(R) batches, which will lead to an out-of-stock > situation in the United States in late April. > Patients in the US are advised to contact their healthcare provider. > Neupro(R) supply is sufficient in other regions. > Brussels, Belgium - March 20, 2008 at 7:00 am CET - UCB announced today that > the company will be recalling Neupro(R) (rotigotine transdermal system) in > the United States and certain batches in Europe. The recall decision resulted > from ongoing monitoring of marketed product, which revealed a deviation from > the approved product specification. As a result, there will be an > out-of-stock situation with Neupro(R) in the United States in late April > 2008. In the European Union and most other regions Neupro(R) supply is > sufficient. > "We have informed the FDA and agreed to actions to inform healthcare > providers and patients," said Iris Loew-Friedrich, MD, PhD, Chief Medical > Officer, UCB. "We advise patients in the US to contact their healthcare > provider to begin the down-titration of Neupro(R) as per the guidelines in > the label. It is strongly advised that patients do not discontinue therapy > abruptly. I also want to emphasize that the issue is not one of product > contamination or toxicity but rather one of possibly reduced clinical > performance of some patches." > Down-titration (reduction of the dose) should be gradual and performed under > medical supervision. Rapid reduction of therapy for Parkinson's disease has > been associated with a symptom complex resembling neuroleptic malignant > syndrome or akinetic crises. > > http://www.genengnews.com/news/bnitem.aspx?name=32425368 > > > __._,_.___ > > Your email settings: Individual Email|Traditional > Change settings via the Web (Yahoo! ID required) > Change settings via email: Switch delivery to Daily Digest | Switch to Fully > Featured > Visit Your Group | Yahoo! Groups Terms of Use | Unsubscribe > > __,_._,___ > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------- This mail sent through http://www.ukonline.net ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn