Print

Print


PARKINSON'S DISEASE NEWS

10th April 2008 - New research
DEMENTIA AND SURVIVAL IN PARKINSON'S DISEASE
Neurology [2008] 70 (13) : 1017-1022 (Buter TC, van den Hout A, Matthews FE, 
Larsen JP, Brayne C, Aarsland D.) Complete abstract

The risk of dementia in Parkinson disease is high, with important clinical 
consequences for people with Parkinson's Disease. However, the absolute risk 
of dementia and how it affects survival in Parkinson's Disease were not 
known. Researchers assessed the prevalence of Parkinson's Disease with 
dementia as people age. Over 60% of people with Parkinson's Disease were 
eventually found to also have dementia. The cumulative incidence of dementia 
was found to steadily increase with age and duration of Parkinson's Disease. 
So for those that live until 90 years of age the likelihood of dementia 
increases to 80% to 90%. Women live with Parkinson's Disease longer than men 
and spend more years with dementia. At the age of 70, a man with Parkinson's 
Disease but no dementia has a life expectancy of 8 years, of which 5 years 
would be expected to be dementia free and 3 years would be expected to be 
with dementia. Although dementia was found to be common in Parkinson's 
Disease, and appear almost inevitable in the oldest of sufferers, no 
comparison was made with the general population to see if people without 
Parkinson's Disease were almost as likely to develop dementia. Parkinson's 
Disease is biochemically distinct from dementia. So there is no inevitable 
reason why they should coincide.

Rayilyn Brown
Board Member AZNPF
Arizona Chapter National Parkinson's Foundation
[log in to unmask] 

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:[log in to unmask]
In the body of the message put: signoff parkinsn