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22nd May 2008 - New research
FATTY ACIDS REDUCE DEPRESSION IN PARKINSON'S DISEASE
Journal of Affective Disorders 2008 May 14; [Epub ahead of print] (da Silva 
TM, Munhoz RP, Alvarez C, Naliwaiko K, Kiss A, Andreatini R, Ferraz AC.) 
Complete abstract
Omega-3 fatty acids are, like vitamins, essential for health and cannot be 
biosynthesized. So they have to be consumed in the diet. Omega-3 fatty acids 
are present in high quantities in some oils, such as fish oil. For more 
information go to Omega-3 fatty acids.  A degree of depression is very 
common in Parkinson's Disease. The effect of fish oil supplementation was 
assessed in people with Parkinson's Disease and depression. Changes in 
depression were measured using three scales : Montgomery-Asberg Rating Scale 
(MADRS), the Clinical Global Impressions Scale (CGI) and Beck Depression 
Inventory (BECK). Patients given fish oil supplements showed a significant 
reduction in depression on two of the three scales. In 42% of patients, 
their symptom scores were more than halved. In 22% of patients, they were 
rid of depression altogether. The authors do not explain how this 
anti-depressant effect was obtained. It can not be by increasing dopamine 
levels, because fatty acids are not involved in dopamine biosynthesis. 
Rather than using fish oil supplements, Omega-3 fatty acids can be better 
supplied by changing over to Canola oil (rapeseed oil) for use in frying and 
salad oil. For more information go to Canola oil (rapeseed oil)

Rayilyn Brown
Board Member AZNPF
Arizona Chapter National Parkinson Foundation
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