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Eye Scans Could Detect First Signs Of Diseases
Laser Devices Could Allow Early Detection Of Diabetes, Alzheimer's, 
Parkinson's
POSTED: 8:45 pm MDT May 18, 2008
UPDATED: 7:42 pm MDT May 20, 2008

More than 46 million Americans live with diabetes, Parkinson's, cataracts 
and Alzheimer's. For some, early detection could lessen the diseases' 
impact, but for others, there is little doctors can do to detect the 
conditions before they progress.
Parkinson's, for example, develops when neurons in the brain become damaged 
or deleted, but the first signs of the disease are not obvious until 80 
percent of these neurons are damaged beyond repair. Other tests, like those 
for diabetes, can be painful and long, requiring patients to drink a syrupy 
liquid, then have their blood drawn.
Your eyes can do a lot more than read and blink. Just by looking into the 
eye, doctors can "see" your heart beat, nutrient levels and even warning 
signs of disease. Researchers from the University of Texas have developed 
laser devices to non-invasively examine the eye to get early detection of 
eye conditions such as cataracts, macular degeneration, glaucoma, and 
retinopathy as well as systemic diseases like diabetes, neurological 
disorders like Alzheimer's and Parkinson's, and osteoporosis.

The eye itself is made up of numerous tissues and layers. When light enters 
the eye through the cornea, it must travel through the tissues of the eye, 
which Texas researchers say are representative of nearly every tissue type 
in the body.
The aqueous region, located between the cornea and the iris, has the same 
components and concentrations as blood serum. Therefore, the concentration 
of glucose in the aqueous mimics the glucose concentration in the blood, 
giving doctors a non-invasive indication of a person's blood glucose 
levels -- vital for diabetes detection. When doctors transmit a laser light 
through the eye, they can determine the glucose levels in the aqueous.
Alzheimer's can be detected using Dynamic Light Scattering -- when light 
beams mix with a system of particles. The amyloid proteins affected in 
Alzheimer's disease can promote aggregation of ocular proteins in the lens. 
When light passes through the eye, it can measure this protein aggregation. 
If Alzheimer's is detected at an early state, patients can perhaps be 
treated for early stages of the disease. The effects of early treatment and 
detection are not yet fully understood.
The need for non-invasive testing methods is great among astronauts 
stationed in outer space for long-term missions. These laser methods, which 
are 200 to 300 times more sensitive than conventional cataract testing 
methods, were tested in space where loose fluids and large testing machines 
cannot be. Their use, however, is just as valuable on the ground as it is in 
space.
Additional Resource:
Vision Research and Human Health Diagnostics Laboratory
(713) 500-3902

Copyright 2008 by TheDenverChannel.com. All rights reserved. This material 
may not be published, broadcast, rewritten or redistributed.
Rayilyn Brown
Board Member AZNPF
Arizona Chapter National Parkinson Foundation
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