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Moneesha I just asked Dr Rajmaran the same question. Mere beti -daughter- has parkinsonism, but we both eat vegetables, tofu, and eggs with generous haldi powder added in our home. Do you think it makes a difference? Angela> Date: Wed, 28 May 2008 17:54:42 +0530> From: [log in to unmask]> Subject: Re: Turmeric for Parkinson's> To: [log in to unmask]> > Amazing! We use turmeric almost every day in our cooking but probably not> in the kinds of quantities that would make a difference.> > NIMHANS in Bangalore is a very reputed institution.> > Moneesha> Wife of Prem 62/56/54? Calcutta, India> > > > On Wed, May 28, 2008 at 2:51 PM, M.Schild <[log in to unmask]> wrote:> > > Turmeric for Parkinson's> >> > Subhra Priyadarshini> > The researchers: Mythri, Bharath, JagathaThe researchers: Mythri, Bharath,> > Jagatha> >> > Curcumin, the wonder compound in turmeric, has found another possible> > therapeutic use — this time for treatment of Parkinson's Disease1.> >> > Researchers conducting experiments on mice have shown that curcumin> > increased> > the content of glutathione (GSH), an anti-oxidant in certain nerve cells of> > the brain that control body movement. The increased GSH protects the brain> > against abnormal accumulation of toxic free radicals that damage the> > mitochondria of these nerve cells triggering off Parkinson's Disease (PD).> >> > "During Parkinson's, there is a gradual death of specific nerve cells> > called> > dopaminergic neurons in the mid-brain. If we understand why these cells> > die,> > we can slow the process down or reverse it by developing better therapies,"> > says M. M. Srinivas Bharath, the lead researcher.> >> > During early PD, there is a significant depletion of GSH leading to> > abnormal> > accumulation of toxic free radicals. These free radicals damage> > mitochondria,> > the powerhouse of the cell, ultimately killing the nerve cells. "So, if we> > could prevent depletion of GSH in mid-brain nerve cells, we could protect> > nerve cells against degeneration," Bharath says.> >> > The team found that selective GSH depletion in mid-brain nerve cells> > damaged> > mitochondria mimicking an early PD condition. To protect against this> > insult,> > they administered curcumin. The compound protected mouse brain and nerve> > cells in culture by increasing the GSH content and protecting against toxic> > free radicals thus exhibiting therapeutic potential in early PD.> >> > To support this conclusion, the team used computer simulations and> > biochemical> > experiments. They simulated disease pathways of PD using mathematics and> > computer modeling to generate a virtual experimental system that gives a> > complete picture of disease cascades and potential therapeutic targets.> > Using> > this 'in silico' model, they corroborated that curcumin could be a> > potential> > therapeutic compound in PD.> >> > The authors of this work are from: Department of Neurochemistry, National> > Institute of Mental Health and Neurosciences, Hosur Road, Bangalore,> > Karnataka, India; Cell works group Inc., Marathahalli, Bangalore & Pierce> > Road, Saratoga, CA, USA.> >> > *> >> > ----------------------------------------------------------------------> > To sign-off Parkinsn send a message to: mailto:> > [log in to unmask]> > In the body of the message put: signoff parkinsn> >> > ----------------------------------------------------------------------> To sign-off Parkinsn send a message to: mailto:[log in to unmask]> In the body of the message put: signoff parkinsn _________________________________________________________________ Give to a good cause with every e-mail. Join the i’m Initiative from Microsoft. http://im.live.com/Messenger/IM/Join/Default.aspx?souce=EML_WL_ GoodCause ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn