For gout - fresh cherries. a work colleague of mine didn't believe it, tried
anyway - 6 weeks later - gout nearly gone & off painkillers.
Quoting rayilynlee <[log in to unmask]>:
> Gout and risk of Parkinson disease
> A prospective study
> Alvaro Alonso, MD, PhD, Luis A. García Rodríguez, MD, MSc, Giancarlo
> Logroscino, MD, PhD and Miguel A. Hernán, MD, DrPH
> From the Department of Epidemiology (A.A., G.L., M.A.H.), Harvard School of
> Public Health, Boston, MA; and Centro Español de Investigación
> Farmacoepidemiológica (L.A.G.R.), Madrid, Spain.
>
> Address correspondence and reprint requests to Dr. Alvaro Alonso, Division
> of Epidemiology and Community Health, School of Public Health, University of
>
> Minnesota, 1300 S. 2nd Street, Minneapolis, MN 55454
>
> Background: Several reports suggest that higher levels of serum uric acid
> are associated with a lower risk of Parkinson disease (PD). None of these
> studies, however, evaluated the potential association between gout, a
> condition characterized by hyperuricemia, and the risk of PD.
>
> Objective: To estimate prospectively the association between gout diagnosis
> and the risk of PD.
>
> Methods: We conducted a case-control study nested in the General Practice
> Research Database, a computerized database that gathers information on more
> than 3 million Britons followed up by their general practitioners. PD cases
> occurring between January 1995 and December 2001 were identified, and
> matched with up to 10 controls by sex, age, practice, and start of
> follow-up. We obtained information on history of gout and use of anti-gout
> medication using the computerized medical records.
>
> Results: During the study period, we identified 1,052 PD cases and 6,634
> controls. Individuals with previous history of gout had a lower risk of
> developing PD (OR 0.69, 95% CI 0.48, 0.99). This association was evident
> among men (OR 0.60, 95% CI 0.40, 0.91) but not among women (OR 1.26, 95% CI
> 0.57, 2.81; p for interaction: 0.11). Initiation of anti-gout medication was
>
> associated with a lower risk of PD (OR 0.57, 95% CI 0.19, 1.70).
>
> Conclusion: Gout is associated with a lower risk of Parkinson disease (PD).
> Our findings provide additional support for a potential link between uric
> acid and PD. Further research is required to explore a potential effect
> modification by sex.
>
> GLOSSARY: GPRD = General Practice Research Database; PD = Parkinson disease.
>
>
>
> -----------------------------------------------------------------------------
---
>
> aalogut{at}alumni.unav.es
>
> Supported by NIH grant R01 HL080644.
>
> Disclosure: The authors report no conflicts of interest.
>
>
> Rayilyn Brown
> Director AZNPF
> Arizona Chapter National Parkinson Foundation
> [log in to unmask]
>
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