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In my case I seem to have increased my predilection for electronic  
"toys" i.e., computers and peripherals. In fact, I have jut had to  
rein mysElf in, having gone a bit overboard lately. On my meagre  
income and state of wealth I could not afford any gambling...

On 27-Jun-08, at 8:18 AM, [log in to unmask] wrote:

> I seem to have developed a pathological urge, not for gambling, but  
> for
> collecting musical instruments. It was always an interest, but since  
> starting
> Mirapex it's gone from 4 to 25 - normal to odd.
> I suspect the compulsion fastens onto an existing urge - I've always  
> disliked
> gambling, which is probably why mine went another way.
>
> Quoting rayilynlee <[log in to unmask]>:
>
>> 26th June 2008 - New research
>> THE PREVALENCE OF PATHOLOGICAL GAMBLING IN PARKINSON'S DISEASE
>> Journal of Gambling Studies 2008 Jun 17; [Epub ahead of print]  
>> (Crockford D,
>> Quickfall J, Currie S, Furtado S, Suchowersky O, El-Guebaly N.)  
>> Complete
>> abstract
>> Pathological gambling has often been identified in people with  
>> Parkinson's
>> Disease treated with dopamine agonists. When somebody takes dopamine
>> agonists such as Ropinirole (Requip) and Pramipexole (Mirapex), they
>> disproportionately stimulate the D3 dopamine receptor, far more  
>> than L-dopa
>> does. This causes arousal in the limbic system, which is where the D3
>> dopamine receptor is primarily located. Given that the limbic  
>> system is
>> connected with the pleasure centre,  the use of certain dopamine  
>> agonists
>> can especially lead to compulsions such as gambling. This study was
>> undertaken to establish the prevalence of pathological gambling in
>> Parkinson's Disease. The prevalence was found to be nearly 10% of  
>> people
>> with Parkinson's Disease. This meant that pathological gambling was  
>> more
>> than 5 times more likely than in people that didn't have Parkinson's
>> Disease. The increased prevalence of pathological gambling in the
>> Parkinson's Disease group was related to dopamine agonist use and  
>> also
>> younger age. Most people suffering from pathological gambling  
>> reported that
>> their gambling increased after diagnosis and starting treatment.
>>
>> Rayilyn Brown
>> Director AZNPF
>> Arizona Chapter National Parkinson Foundation
>> [log in to unmask]
>>
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