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I seem to have developed a pathological urge, not for gambling, but for collecting musical instruments. It was always an interest, but since starting Mirapex it's gone from 4 to 25 - normal to odd. I suspect the compulsion fastens onto an existing urge - I've always disliked gambling, which is probably why mine went another way. Quoting rayilynlee <[log in to unmask]>: > 26th June 2008 - New research > THE PREVALENCE OF PATHOLOGICAL GAMBLING IN PARKINSON'S DISEASE > Journal of Gambling Studies 2008 Jun 17; [Epub ahead of print] (Crockford D, > Quickfall J, Currie S, Furtado S, Suchowersky O, El-Guebaly N.) Complete > abstract > Pathological gambling has often been identified in people with Parkinson's > Disease treated with dopamine agonists. When somebody takes dopamine > agonists such as Ropinirole (Requip) and Pramipexole (Mirapex), they > disproportionately stimulate the D3 dopamine receptor, far more than L-dopa > does. This causes arousal in the limbic system, which is where the D3 > dopamine receptor is primarily located. Given that the limbic system is > connected with the pleasure centre, the use of certain dopamine agonists > can especially lead to compulsions such as gambling. This study was > undertaken to establish the prevalence of pathological gambling in > Parkinson's Disease. The prevalence was found to be nearly 10% of people > with Parkinson's Disease. This meant that pathological gambling was more > than 5 times more likely than in people that didn't have Parkinson's > Disease. The increased prevalence of pathological gambling in the > Parkinson's Disease group was related to dopamine agonist use and also > younger age. Most people suffering from pathological gambling reported that > their gambling increased after diagnosis and starting treatment. > > Rayilyn Brown > Director AZNPF > Arizona Chapter National Parkinson Foundation > [log in to unmask] > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------- This mail sent through http://www.ukonline.net ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn