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People get flustered when tested (I do, anyway) - hope researchers allowed for this - the "cognitive impairment" may've been plain fear. Quoting "schild.m" <[log in to unmask]>: > Mild cognitive impairment is common even in newly diagnosed PD patients, and > > non-impaired patients are at higher risk than controls to develop MCI, > according to two new studies. > > Aarsland et al. examined cognitive function in 181 newly diagnosed PD > patients > without dementia or depressive disorder. Mean duration of symptoms was 2.3 > years. As a group, PD patients were impaired on all neuropsychological tests > > compared to controls. Mild cognitive impairment (defined as a z score > below -1.5 in at least one cognitive domain out of verbal memory, > visuospatial function, and executive function) was found in 17.7% of PD > patients, versus 8.2% of age-matched controls (p<0.001). > > In those PD patients with MCI, impairments were as follows: > single-domain non-amnestic MCI 62.5% > multiple-domain non-amnestic 9.4% > single-domain amnestic 21.9% > multiple-domain, amnestic MCI 6.3% > > "All cognitive domains assessed were impaired, but the majority of MCI had a > > non-memory type," the authors conclude. "Cognitive impairment should be > considered in PD even at the time of diagnosis." > > Adler et al. prospectively evaluated 44 PD patients, 72 tremor patients, and > > 164 controls, all with similar ages (mean 77-80 years) and education levels > and without MCI. Median follow-up time was 3.1 years. After controlling for > sex differences among the groups, the adjusted 5-year incidence of conversion > > to MCI was 50% for PD, 19% for tremor, and 17% for controls. The hazard ratio > > was 3.7 for PD vs. tremor and 3.0 for PD vs. controls. The risk for men was > twice that as for women. > > > Prevalence and profile of mild cognitive impairment in early, untreated > Parkinson's disease - a community-based study > D. Aarsland, K. Bronnick, J.P. Larsen, O.B. Tysnes, G. Alves > 257;S88 > > Parkinson's disease increases the risk for developing mild cognitive > impairment > C.H. Adler, D. Connor, M. Sabbagh, H. Shill, J. Hentz, V. Evidente, P. > Mahant, > J. Samanta, S. Burns, A. Ahmed, E. Driver-Dunckley, L. Vedders, B. Noble, J. > > Caviness > 292;S100 > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------- This mail sent through http://www.ukonline.net ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn