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HALLUCINATIONS IN parkinson's disease
Practical Neurology [2008] 8 (4) : 238-241 (Poewe W.) Complete abstract
Visual hallucinations occur in up to 40% of people with Parkinson's disease. 
However, hallucinations are not actually due to Parkinson's Disease. Age and 
cognitive decline are the most important intrinsic risk factors, but 
hallucinations are often triggered by conditions such as infection and 
dehydration. The single most important trigger, however, is the use of  CNS 
drugs, especially drugs for Parkinson's Disease. While hallucinations and 
psychosis can be triggered by amantadine and anticholinergics, they are more 
commonly experienced after changes in dopaminergic drugs. Dopamine agonists 
have the greater potential to induce hallucinations compared with L-dopa. 
Attempting to reduce Parkinson's Disease drugs is an important part in the 
management of these symptoms, but atypical neuroleptics like clozapine or 
quetiapine are often also used. Visual hallucinations in Parkinson's disease 
patients with dementia can also be improved by treatment with the 
cholinesterase inhibitor rivastigmine.

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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