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Test for Parkinson's being developed
Published: Aug. 6, 2008 at 12:10 PM

CHESTER, N.J., Aug. 6 (UPI) -- A minimally invasive technology is being 
developed to diagnose Parkinson's disease, U.S. and Canadian researchers 
said.
In the study, researchers Molecular Biometrics, LLC used spectroscopy to 
develop a metabolic profile -- or chemical signatures -- of biological 
markers for Parkinson's disease. There is currently no definitive laboratory 
diagnostic for Parkinson's disease.
"The lack of an objective biomarker to aid diagnosis and therapeutics 
development is one of the single greatest challenges facing the Parkinson's 
research field," Katie Hood of The Michael J. Fox Foundation Parkinson's 
Research said in a statement.
In the study, 52 patients, 20 with mild or moderate stages of Parkinson's 
disease and 32 age-matched control subjects had whole blood samples analyzed 
using near-infrared spectroscopy and Raman spectroscopy methods.
The data from this study, published Biomarkers in Medicine, showed that the 
two independent biospectroscopy measurement techniques yielded similar and 
consistent results. In differentiating Parkinson's disease patients from the 
control group, Raman spectroscopy achieved a sensitivity of 74 percent and 
specificity of 72 percent, with eight false positives and four false 
negatives.
Near-infrared spectroscopy achieved a sensitivity of 74 percent and 
specificity of 76 percent, with four false positives and five false 
negatives.

© 2008 United Press International, Inc. All Rights Reserved.

Rayilyn Brown
Director AZNPF
Arizona Chapter National Parkinson Foundation
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